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Record W1986034855 · doi:10.1093/brain/awh544

The field defects of anterior temporal lobectomy: a quantitative reassessment of Meyer's loop

2005· article· en· W1986034855 on OpenAlexfundno aff
Jason J.S. Barton, Rebecca Hefter, Bernard Chang, Don Schomer, Frank W. Drislane

Bibliographic record

VenueBrain · 2005
Typearticle
Languageen
FieldNeuroscience
TopicVestibular and auditory disorders
Canadian institutionsnot available
FundersNational Institute of Mental HealthMichael Smith Health Research BC
KeywordsAnterior temporal lobectomyQuadrant (abdomen)Dissection (medical)AnatomyMedicineTemporal lobeSurgery

Abstract

fetched live from OpenAlex

Temporal lobectomy is often complicated by superior quadrantanopia. The relation of field loss to sagittal resection length can inform us about the functional anatomy of Meyer's loop, with ramifications for surgical planning. However, the literature has produced highly variable results. We studied 29 patients with anterior temporal lobectomies using Goldmann perimetry. 24 patients had post-operating neuroimaging, with which we assessed resection length relative to each patient's temporo-occipital dimensions. For the field defect we calculated the proportion of area lost for three isopters. We found a significant correlation between resection size and field loss for both nasal and temporal defects. Linear regressions suggested an anterior limit of Meyer's loop at 24 to 28 mm from the anterior temporal pole, and involvement of the lower quadrant when resections reached 70 to 79 mm, with significant inter-subject variability. The nasal defect was 15% greater than the temporal defect for all degrees of quadrantanopia, with no difference between right and left hemispheres. Macular involvement began when field defects reached 61% of quadrant area, corresponding to a resection of about 58 mm. Patterns of field loss showed that the lower margins were most often horizontal or with a slight slope towards fixation, rather than true wedge defects. We conclude that field loss is related to resection length and that Meyer's loop extends more anteriorly than estimated in traditional surgical studies, in agreement with modern MRI and dissection studies. The patterns of field loss support a revised retinotopic model in which the most anterior fibers of Meyer's loop represent the superior field, not the vertical meridian as traditionally proposed.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.044
Threshold uncertainty score0.227

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.322
Teacher spread0.302 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations81
Published2005
Admission routes1
Has abstractyes

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