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Record W1986613648 · doi:10.1016/j.arthro.2013.07.169

Paper #164: Quantitative 3D MRI as a Valid Endpoint for Randomized Clinical Trials in Cartilage Repair and its Correlation with Repair Tissue Collagen Architecture

2013· article· en· W1986613648 on OpenAlexaff
Matthew S. Shive, William D. Stanish, Robert G. McCormack, Francisco Forriol, Nick Mohtadi, Stéphane Pelet, Jacques Desnoyers, José G. Tamez‐Peña, Saara Tötterman, Adele Changoor, Alex Yaroshinsky, Alberto Restrepo

Bibliographic record

VenueArthroscopy The Journal of Arthroscopic and Related Surgery · 2013
Typearticle
Languageen
FieldMedicine
TopicOsteoarthritis Treatment and Mechanisms
Canadian institutionsPiramal (Canada)
Fundersnot available
KeywordsCartilageMedicineLesionClinical trialClinical endpointSurgeryRadiologyPathologyAnatomy

Abstract

fetched live from OpenAlex

Standardized quantitative 3D MRI was used in a multicenter clinical trial and demonstrated structural superiority of BST-CarGel® treatment over microfracture with regards to both the quantity and quality of repair cartilage. Such improved repair cartilage structure may predict superior durability and sustained clinical benefit. T2 MRI correlated with both PLM and the degree of lesion filling.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.083
metaresearch head score (Gemma)0.083
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.917
Threshold uncertainty score0.439

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0830.083
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0030.003
Bibliometrics0.0010.001
Science and technology studies0.0010.002
Scholarly communication0.0020.002
Open science0.0010.001
Research integrity0.0040.002
Insufficient payload (model declined to judge)0.0110.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.349
Teacher spread0.316 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designObservational
DomainMethods
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2013
Admission routes1
Has abstractyes

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