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Repeat prescribing: which diagnoses, which drugs?

2000· article· en· W1986997842 on OpenAlexaff
J. P. Connolly, Hugh McGavock

Bibliographic record

VenuePharmacoepidemiology and Drug Safety · 2000
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicPharmacovigilance and Adverse Drug Reactions
Canadian institutionsQueen's University
Fundersnot available
KeywordsMedicinePharmacoepidemiologyMedical diagnosisIntensive care medicinePharmacologyMedical prescriptionRadiology

Abstract

fetched live from OpenAlex

Background-Repeat prescribing should be limited to drugs which are to be prescribed on a long-term basis to patients whose conditions are stable. Early studies were based on small sample sizes. The definition of repeat prescribing has not been consistent and interpractice variation in repeat prescribing has not been described.Aims-To describe the diagnostic categories and anatomical groups associated with repeat prescriptions; to describe interpractice variation associated with repeat prescribing and to describe the repeat to consultation ratio for the most frequently prescribed diagnoses and drugs.Method-Doctors from a stratified quota sample of 22 Northern Ireland practices recorded their perceived diagnosis for every consultation and for every repeat prescription over a 2-week period.Results-The diagnostic categories significantly associated with repeat prescriptions were digestive, cardiovascular, neurological, psychiatric and metabolic ( p < 0.0001). The anatomical drug categories significantly associated with repeat prescriptions were gastrointestinal drugs, cardiovascular drugs, central nervous system drugs, dressings and appliances (p < 0.0001). There was wide interpractice variation in repeat prescribing (both overall and for individual anatomical groups) and associated diagnoses. High repeat to consultation ratios were recorded for ranitidine, temazepam and diazepan.Conclusions-Wide interpractice variation in repeat prescribing and associated diagnoses revealed poor consensus among practices. Therefore, the approach to the management of common conditions - whether to consult or issue a repeat prescription - was not uniform. The implications of these findings require further research. Commonly occurring diagnoses and drugs had unacceptably high repeat to consultation ratios. Copyright (c) 2000 John Wiley & Sons, Ltd.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.024
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.013
Threshold uncertainty score0.027

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.024
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.002
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.079
GPT teacher head0.422
Teacher spread0.343 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2000
Admission routes1
Has abstractyes

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