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Development of an Orbital Endoscope for Use with the Free Electron Laser

2004· article· en· W1987041229 on OpenAlexaff
Louise A. Mawn, Jin-Hui Shen, David Jordan, Karen M. Joos

Bibliographic record

VenueOphthalmic Plastic and Reconstructive Surgery · 2004
Typearticle
Languageen
FieldMedicine
TopicMeningioma and schwannoma management
Canadian institutionsUniversity of Ottawa
FundersNational Eye Institute
KeywordsEndoscopeMedicineCadaverEndoscopyForcepsFree-electron laserSurgeryHuman eyeOpticsLaserBiomedical engineeringPhysics

Abstract

fetched live from OpenAlex

PURPOSE: To explore the feasibility of designing, constructing, and testing an orbital endoscope for use with the free electron laser (FEL). METHODS: An experimental study with an author-designed laser delivery system through an endoscope was conducted. Two adult pig cadavers and 6 fresh human cadavers had orbital endoscopy performed to develop a method of optic nerve sheath fenestration (ONSF) with the FEL. Twelve orbits were used to develop the surgical procedure by comparing visualization media and surgical technique. In the first 7 trials, a different variable was changed; the procedure was then refined in the human cadaver experiments. An ONSF was performed with the FEL (6.45 microm, 30 Hz, 2 to 3 mJ, 250-microm spot size) through a glass hollow wave guide introduced through an endoscope in 4 human cadaver orbits. RESULTS: Visualization of the orbital structures was clearest with carbon dioxide; sodium hyaluronate did not displace the fat, and saline hydrated the orbital fat. Biopsy forceps alone did not produce a dural window in the four trials that used the forceps. A dural window was made by using the FEL through a glass hollow wave guide adapted to the Olympus HYF-XP endoscope in the second, third, fifth, and sixth human trials with the FEL. Histologic evidence of the ONSF was produced. CONCLUSIONS: A hollow wave guide capable of transmitting the FEL through an endoscope was successfully constructed. ONSF with the FEL applied through an endoscope is technically feasible. Additional studies are currently examining techniques to improve intraorbital endoscopy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.001
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.241
Teacher spread0.216 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations12
Published2004
Admission routes1
Has abstractyes

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