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Record W1988219601 · doi:10.1186/1742-4690-7-s1-i3

The influenza challenge

2010· article· en· W1988219601 on OpenAlexaboutno aff
Tim Nguyen, Sylvie Briand

Bibliographic record

VenueRetrovirology · 2010
Typearticle
Languageen
FieldMedicine
TopicInfluenza Virus Research Studies
Canadian institutionsnot available
Fundersnot available
KeywordsPandemicInfluenza A virus subtype H5N1PreparednessPublic healthOutbreakInternational Health RegulationsMedicineOseltamivirDiseaseInfectious disease (medical specialty)VirologyPolitical scienceVirusCoronavirus disease 2019 (COVID-19)

Abstract

fetched live from OpenAlex

The presentation aims at introducing the various challenges faced at global level during the first pandemic of the 21st century. On 25 April 2009, Mexico, under the International Health Regulations (2005) (IHR (2005)), notified the World Health Organization (WHO) about an outbreak of influenza-like illness. The responsible virus was identified a few days later by a WHO Collaborating Centre for Reference and Research on Influenza and a reference laboratory in Canada. This was the first reported event related to Influenza A (H1N1). In less than nine weeks, the pandemic virus spread in the six WHO regions. On 11 June 2009, WHO announced a pandemic phase 6. Because of the threat posed by the re emergence of A(H5N1)virus in 2003 in Asia, most of the influenza experts and modellers were predicting that the next pandemic would start in Asia with similar characteristic as the H5N1 disease currently observed with a high case fatality ratio. One of the lessons learned is that predictions are very difficult when related to influenza viruses due their unpredictable evolution and the complexity of factors leading to pandemic. The pandemic (H1N1) 09 is challenging in many aspects: firstly, the uncertainty about the evolution of the virus makes mid term preparedness and planning difficult. Secondly, the weakness of some surveillance system does not allow an easy monitoring of the disease and its spread. The oseltamivir resistance monitoring has also been difficult in some parts of the world. Thirdly, the modern communications means enable rumours to spread faster than ever. Public health authorities have to include risk communication in their strategy to respond to the outbreak. The nature of this pandemic with moderate severity and very rapid spread imposed to revise national pandemic preparedness plans during the course of the event. The public and the media often misunderstood the rational for the modification. The international community has responded quite well to the pandemic threat. In particular, countries have been especially collaborative regarding the exchange of information and the global access to supplies such as vaccine and antiviral drugs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.082
Threshold uncertainty score0.276

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.006
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.000
Science and technology studies0.0020.001
Scholarly communication0.0070.006
Open science0.0010.005
Research integrity0.0080.008
Insufficient payload (model declined to judge)0.0820.040

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.063
GPT teacher head0.388
Teacher spread0.325 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2010
Admission routes1
Has abstractyes

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