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DIFFERENCES IN LEAN TISSUE MASS AND STRENGTH BETWEEN PATIENTS WITH CROHN??S DISEASE AND HEALTHY CONTROLS

2003· article· en· W1988775475 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
aboutThe title or abstract carries a Canadian signal from the geographic lexicon.

Bibliographic record

VenueMedicine & Science in Sports & Exercise · 2003
Typearticle
Languageen
FieldMedicine
TopicMicroscopic Colitis
Canadian institutionsUniversity of Saskatchewan
Fundersnot available
KeywordsCrohn's diseaseLean body massMedicineInternal medicineDiseaseGastroenterologyBench pressInflammatory bowel diseasePhysical therapyBody weightResistance training

Abstract

fetched live from OpenAlex

Crohn's Disease is an inflammatory bowel disease that may have an effect on lean tissue mass and strength due to reduced nutrition or corticosteroid useage. There is controversy as to whether patients in remission from Crohn's Disease have reduced lean tissue mass and strength. PURPOSE To compare lean tissue mass and strength in subjects with Crohn's Disease to healthy controls adjusting for age, sex, and height. METHODS Subjects in remission from Crohn's Disease (n=25;age=44y) were recruited from an ongoing study. Lean tissue and fat mass were assessed using dual energy X-ray absorptiometry and compared to healthy controls from a pre-existing database (n=174; age=44y). Bench press and leg press one-repetition maximum strength was measured in a subset of these Crohn's Disease subjects (n=14) and compared to the controls (n=135,bench press; n=136,leg press). All comparisons were made using ANCOVA, adjusting for age, sex, and height. RESULTS Crohn's Disease subjects had lower lean tissue mass (39.7 vs. 45.1 kg) and higher fat mass (34.9 vs. 23.9 kg) compared to controls (p < 0.05). Leg press (106 vs. 139 kg) and bench press (61.5 vs. 65.5 kg) strength were also lower in Crohn's Disease subjects compared to controls (p < 0.05). CONCLUSION Subjects with Crohn's Disease have lower lean tissue mass and strength and higher fat mass when compared to healthy controls. The results may be useful in determining appropriate exercise training programs in order to reverse the effects of the disease. Supported by the University of Saskatchewan President's NSERC fund.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.023
Threshold uncertainty score0.653

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.277
Teacher spread0.265 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it