Impact of diet deprivation and subsequent over-allowance during prepuberty. Part 2. Effects on mammary gland development and lactation performance of sows1
Bibliographic record
Abstract
The impact of diet deprivation and subsequent over-allowance in prepubertal gilts on their mammary development and mammary gene expression at the end of gestation and their lactation performance over 2 parities was determined. Seventy-seven gilts were reared under a conventional (control, CTL; n = 41) or an experimental (treatment, TRT; n = 36) dietary regimen. The experimental regimen provided 70 (restriction diet, RES) and 115% (over-allowance diet, OVER) of the protein and DE contents provided by the CTL diet. Experimental diets were fed ad libitum starting at 27.7 ± 3.4 kg of BW as follows: 3 wk RES, 3 wk OVER, 4 wk RES, and 4 wk OVER. All gilts were bred, and 34 were slaughtered on d 110 of gestation (18 CTL and 16 TRT) to collect mammary tissue for compositional analyses and gene expression measurements. Remaining gilts (23 CTL and 20 TRT) were maintained for 2 parities, and litter performance data were obtained. Blood samples for hormonal and metabolite assays were obtained on d 110 of gestation from all sows slaughtered at that time and from 14 sows per treatment on d 2 and 17 of lactation in the first parity. Milk samples were obtained from these same sows on d 17 of lactation in both parities. There was a tendency for mammary parenchymal tissue to contain less protein in TRT than CTL sows (P < 0.10), and relative mRNA abundance of the signal transducer and activator of transduction 5B gene was increased in parenchyma from TRT sows (P < 0.05). Circulating prolactin (P < 0.05) and milk lactose concentrations (P < 0.01) were less, whereas milk protein content was greater (P < 0.05) in TRT sows than CTL sows on d 17 of lactation. Nevertheless, growth rate of suckling piglets over the first 2 parities was unaffected by treatment. In conclusion, the use of a diet deprivation and over-allowance regimen in the growing-finishing period did not have beneficial effects on mammary gene expression or on sow and piglet performance.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".