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Hypoxia: Into the Next Millennium

2001· article· en· W1991618067 on OpenAlexaboutno aff
Rob Hamilton

Bibliographic record

VenueWilderness and Environmental Medicine · 2001
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicHigh Altitude and Hypoxia
Canadian institutionsnot available
Fundersnot available
KeywordsHypoxia (environmental)High-altitude pulmonary edemaEffects of high altitude on humansTributeMedicineInternal medicineHistoryChemistryArt historyPulmonary edemaLungAnatomy

Abstract

fetched live from OpenAlex

Every other winter, an eclectic and highly qualified group of mountaineers, clinicians, high-altitude scientists, and bench researchers who have an interest in hypoxia gather in the Canadian Rocky Mountains to socialize, ski, and, of course, discuss the latest research on the effects of low oxygen tension on biological systems. This book is the proceedings of the 11th International Hypoxia Symposium, held in 1999 in Jasper National Park. It is an interesting and informative compendium of articles for those who wish to understand where the frontiers are in the study of hypoxia. The book begins with a fascinating paper on the career and research of Herb Hultgren (1917–1997), a Stanford cardiologist and pioneer in the study of high-altitude pulmonary edema. It finishes with a tribute to Niels Lassen (1926–1997), a premier researcher into the effects of altitude on cerebral blood flow and functional brain mapping. In between is a well-chosen mix of clinical and basic science monographs from luminaries in the field, which quickly brings the reader up-to-date on the “state-of-the-art” on hypoxia. The first several chapters are dedicated to mountain medicine, with subsequent sections on high-altitude pulmonary edema, the effects of hypoxia on the blood-brain barrier and the brain, lactate metabolism and vascular growth, and human physiology in extreme hypoxia. The volume also includes abstracts of original research presented at the symposium's oral and poster sessions. As a group, these presentations give deep insight into the work being done in the field and by whom, and they are an excellent collection to serve as a springboard for further reading and research. While this is a book for those with a special interest in hypoxia, others may find it useful. It is not light reading and isn’t meant to be read cover to cover, but it is an excellent way to get acquainted with what is known about the subject, on-going research, and who is doing it. I highly recommend this book if you have even a passing interest in high-altitude hypoxia or hypoxia from other causes. It may even inspire you to be a part of the next symposium.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.899
Threshold uncertainty score0.320

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.221
Teacher spread0.210 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2001
Admission routes1
Has abstractyes

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