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Record W1993399662 · doi:10.1118/1.3181494

SU‐FF‐T‐23: Analysis of Dosimetric Quantities Associated with Partial Breast Brachytherapy

2009· article· en· W1993399662 on OpenAlexaff
Desmond A. O’Farrell, Adam Steward, Marie-Lynn Racine, Yulia Lyatskaya, Phillip M. Devlin, Robert A. Cormack

Bibliographic record

VenueMedical Physics · 2009
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBreast Cancer Treatment Studies
Canadian institutionsHôpital Maisonneuve-Rosemont
Fundersnot available
KeywordsSupine positionBrachytherapyDosimetryNuclear medicineRadiation treatment planningProne positionMedicineLung volumesRadiation therapyRadiologyLungSurgeryInternal medicine

Abstract

fetched live from OpenAlex

Purpose: Radiation dose to the heart and lung are a concern in accelerated partial breast irradiation (APBI). This work presents an analysis of the metrics inherent to high dose rate APBI using a brachytherapy source. Method and Materials: Five patients receiving APBI brachytherapy, and 4 patients, who were simulated in both supine and prone position for XRT, were contoured. Dose to the heart and lung were calculated for all potential dwell locations within the contoured breast for a range of potential dwell times. Summary volume and dose metrics were calculated for heart and lung as function of minimum distance (dmin) to the normal structures. The distribution of minimum distances was then compared for the prone and supine patients. Results: Dose metrics such as the D10cc were patient specific and not well suited to parameterization. Volume metrics such as V10Gy tend to have similar behavior and may be characterized as a function of dmin. The characterization provides a measure of the normal tissue dose parameters that are achievable as a function of dmin. While prone position shift the distribution of lung to breast distances towards greater value, the distribution of heart to breast distances is shifted to smaller distances. Conclusion: Characteristic curves of the achievable volume metrics as a function of minimum distance from implant to normal structures are presented. These curves may be helpful in the decision to use APBI brachytherapy based on the location of the cavity. The choice of treatment position affects the distribution of breast tissue, though the effect on distance to heart and lung differs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.262
Teacher spread0.253 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2009
Admission routes1
Has abstractyes

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