Myeloid Sarcoma Presenting as an Anterior Mediastinal Mass Invading the Pericardium
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Myeloid sarcoma is a tumor formed by extramedullary accumulation of myeloblasts or immature myeloid cells. These tumors can develop in lymphoid organs, bone, skin, soft tissue, and other organs, and may precede or occur concurrently with acute myeloid leukemia. This is a case of a 42-year-old man who presented with a 2-week history of cough and shortness of breath on exertion. A computed tomography (CT) scan showed a large mediastinal mass and pericardial effusion. An F-18 fluorodeoxyglucose positron emission tomography-CT scan showed intense fluorodeoxyglucose (FDG) uptake in the mediastinal mass with invasion of the parietal pericardium. Biopsy of the mediastinal mass and pericardium revealed myeloid sarcoma. The pericardial effusion was drained and the patient was treated with high-dose cytosine arabinoside (HiDAC) chemotherapy. A follow-up positron emission tomography-CT was done 2 months after the last cycle, showing poor response to therapy and significant progression of disease with invasion through the anterior chest wall. Myeloid sarcoma can be added to the differential diagnosis of F-18 FDG avid anterior mediastinal masses, as well as F-18 FDG uptake in the pericardium.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.021 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.002 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it