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Record W1993579584 · doi:10.1118/1.2241626

TU‐E‐224A‐05: Intermediate Energy X‐Ray Photons (0.2 – 1.0 MeV) for Radiosurgery: Producing a Beam and Measurement of Radiological Penumbra

2006· article· en· W1993579584 on OpenAlexaff
Brian Keller, Lauren O'Malley, D Beachey, J Presutti, Jean‐Philippe Pignol

Bibliographic record

VenueMedical Physics · 2006
Typearticle
Languageen
FieldPhysics and Astronomy
TopicAdvanced Radiotherapy Techniques
Canadian institutionsSunnybrook Health Science Centre
Fundersnot available
KeywordsPenumbraLinear particle acceleratorPhysicsImaging phantomIonization chamberCollimated lightMonte Carlo methodRadiosurgeryOpticsBeam (structure)Nuclear medicineCyberknifePhotonPercentage depth dose curveCollimatorMaterials scienceIonizationLaserRadiation therapyMedicineMathematicsRadiology

Abstract

fetched live from OpenAlex

Purpose: The main advantage of stereotactic radiosurgery is the steep dose gradient associated with the intracranial dose distribution. We are examining the effects of x‐ray energy on penumbra and dose gradient. Specifically, we are exploring the reduction in radiological penumbra for intermediate energy x‐ray photons (0.2–1.0 MeV) or so called IEP's. The purpose of this work is two‐fold: 1.) to produce an IEP beam using a medical linear accelerator and 2.) to examine the radiological penumbra associated with this beam. Method and Materials: A Siemens medical linear accelerator was adapted to produce IEP's. PDD measurements versus depth (SSD=100cm,FS=2×2cm2) were done in solid water using a Markus parallel plate ionization chamber (PTW Freiburg). These were compared with Monte Carlo computer simulations (MCNP‐4C). Monte Carlo involved generating x‐ray spectra that impinged upon a SW phantom. A penumbra measurement device (consisting of a half‐beam block) was constructed to examine radiation beam edge profiles using film (Gafchromic EBT) at SSD=100cm,FS=1.1cm2 and depth=2cm. In a separate experiment, film irradiations were done collimating a 3×3mm2 beam using a 10cm thick brass block flush with the SW surface. In all cases, the geometric penumbra (due to the finite source size) was made negligible by having the collimation very close to the phantom. A high‐resolution digital microscope (Axiomat) was used to acquire film profiles. Results: Measured PDD values were 55.4%(surface), 62.6%(5cm), and 34.7%(10cm). Monte Carlo PDD's compared with measurement suggest a nominal 800kV x‐ray beam. For the half‐beam block, the 80%–20% film edge profiles were 0.345mm (IEP) and 2.10mm (6MV). For the 3×3mm2 field, there was a 5‐fold reduction in radiological penumbra (IEP vs. 6MV). Conclusions: A novel intermediate energy photon beam (of nominal energy 800kV) has been produced using a conventional linear accelerator. There is a substantial reduction in radiological penumbra when using IEP's with small fields.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.023

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0010.000
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0070.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.251
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2006
Admission routes1
Has abstractyes

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