Control of Breathing in Patients with Chronic Obstructive Lung Diseases and Secondary Polycythemia after Venesection
Bibliographic record
Abstract
Using the mouth occlusion pressure technique, we have studied the control of breathing in 10 hypercapnic patients with chronic obstructive pulmonary diseases and polycythemia before and after venesection. The mean hematocrit value was 59.9 +/- 5.5% which, following venesection (approximately 1,200-1,600 cm3 of blood was removed from each patient over three consecutive days), fell to 44.4 +/- 2.2%. Respiratory drive, expressed as P0.1 (mouth occlusion pressure 0.1 s after the onset of occluded inspiration at functional residual capacity) and as mean inspired flow (VT/TI), was diminished after venesection (p less than 0.001 and p less than 0.05); in contrast to that, we found no changes in respiratory timing (TI and TI/Ttot). The arterial PCO2 was decreased (p less than 0.001) and arterial PO2 was increased after venesection, these improvements are mainly attributed to decreased dead space ventilation (p less than 0.05). It seems that the improvements of blood gases after venesection is probably responsible for the decrease in respiratory drive.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".