Classification of Intrinsically Disordered Regions and Proteins
Why is this work in the frame?
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Machine scores (provisional)
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
- Teacher spread
- 0.289 · how far apart the two teachers sit on this one work
- Validation status
score_only:v0-immature-baseline· verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it
Abstract
Characterization of unannotated and uncharacterized protein segments is expected to lead to the discovery of novel functions as well as provide important insights into existing biological processes. In addition, it is likely to shed new light on molecular mechanisms of diseases that are not yet fully understood. The classical concept implies that protein sequence defines structure, which in turn determines function; that is, function can be inferred from the sequence and its structure. Even when protein sequences diverge during evolution, for example, after gene duplication, the overall fold of their structures remains roughly the same. Therefore, structural similarity between proteins can reveal distant evolutionary relationships that are not easily detectable using sequence-based methods.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
The record
- Venue
- Chemical Reviews
- Topic
- Protein Structure and Dynamics
- Field
- Biochemistry, Genetics and Molecular Biology
- Canadian institutions
- University of TorontoUniversity of British Columbia
- Funders
- Biotechnology and Biological Sciences Research CouncilNational Cancer InstituteNational Institute of General Medical SciencesMedical Research CouncilCanadian Institutes of Health ResearchU.S. Public Health Service
- Keywords
- MemphisLibrary scienceColumbia universityBoulevardBiologySociologyHistoryMedia studiesComputer scienceArchaeology
- Has abstract in OpenAlex
- yes