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Neurodevelopmental anomalies of the hippocampus in rats exposed to weak intensity complex magnetic fields throughout gestation

2012· article· en· W1997499243 on OpenAlexafffund
Neil M. Fournier, Quoc Hao Mach, Paul D. Whissell, Michael A. Persinger

Bibliographic record

VenueInternational Journal of Developmental Neuroscience · 2012
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicFractal and DNA sequence analysis
Canadian institutionsUniversity of TorontoLaurentian University
FundersCanadian Institutes of Health Research
KeywordsHippocampal formationHippocampusIntensity (physics)Prenatal exposureDysgenesisGestationNeuroscienceEndocrinologyInternal medicinePsychologyBiologyMedicinePhysicsAnatomyPregnancyOpticsGenetics

Abstract

fetched live from OpenAlex

There has been increasing interest on the possible harmful effects of prenatal exposure to magnetic fields. To investigate the effect of weak intensity magnetic fields on the prenatal brain, pregnant Wistar rats were continuously exposed to one of four intensities (reference: 5-20 nT; low 30-50 nT; medium 90-580 nT; high 590-1200 nT) of a complex magnetic field sequence designed to interfere with brain development. As adults, rats exposed to the low-intensity (30-50 nT) complex magnetic field displayed impairments in contextual fear learning and showed anomalies in the cytological and morphological development of the hippocampus. In particular, low-intensity exposures resulted in a reduction in overall hippocampal size and promoted subtle dysgenesis of the CA1 and CA3 regions. In contrast, exposure to weaker or stronger intensities of the same complex magnetic field pattern did not interfere with hippocampal development or fear behavior. These findings suggest that prenatal exposure to complex magnetic fields of a narrow intensity window during development can result in subtle but permanent alterations in hippocampal microstructure and function that can have lasting effects on behavior.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.278
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations10
Published2012
Admission routes2
Has abstractyes

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