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Record W1997749250 · doi:10.1159/000114604

Acute Effects of ECT on the Cerebral Circulation in Man

2008· article· en· W1997749250 on OpenAlex
John W. Lovett Doust, R. Barchha, R.S.Y. Lee, Matthew Little, J.S. Watkinson

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueEuropean Neurology · 2008
Typearticle
Languageen
FieldNeuroscience
TopicNeuroscience and Neural Engineering
Canadian institutionsCentre for Addiction and Mental Health
Fundersnot available
KeywordsAnesthesiaAtropineElectroconvulsive therapyHemodynamicsCerebral circulationDepression (economics)MedicinePsychology

Abstract

fetched live from OpenAlex

The acute cerebral haemodynamic effects of modified ECT were monitored by electrical impedance piethysmography in four patients with schizophrenia and three with depression. A total of 20 recordings were made on these patients; of these, 19 involved the following segments, in sequence: a rest period of 25–115 min, a short period in which Atropine, Brietal, and succinylcholine were given by injection, administration of the ECT, monitoring of post-ECT effects for 10 min, and, finally, a recovery period of up to 120 min was recorded. An identical procedure, save for the omission of ECT in one of the patients, formed the 20th recording. Results were considered significant if they were given by a majority of the 19 ECT recordings. No impedance changes took place during the pre-drug resting period nor following the pre-medication drugs. The acute effects of ECT were shown by electrical impedance changes during the 10 min immediately following it. These implied a surging increase in CBF and persisted during the recovery phase. No such changes occurred when ECT was omitted, and the results suggested that these cerebral circulatory changes formed part of the therapeutic action of ECT.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.277
Threshold uncertainty score0.384

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.221
Teacher spread0.194 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it