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Record W1998967504 · doi:10.1139/v01-122

Quinoxaline-1,2,3-dithiazolyls Synthesis, EPR characterization, and redox chemistry

2001· article· en· W1998967504 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

fundA Canadian funder is recorded on the work.
venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueCanadian Journal of Chemistry · 2001
Typearticle
Languageen
FieldChemistry
TopicSynthesis and Biological Evaluation
Canadian institutionsnot available
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsChemistryElectron paramagnetic resonanceMonoclinic crystal systemRadicalIodideOrthorhombic crystal systemOxidizing agentCrystallographyRedoxQuinoxalineIsonicotinamidePyrazineCrystal structureMedicinal chemistryStereochemistryInorganic chemistryMoleculeOrganic chemistryHydrogen bond

Abstract

fetched live from OpenAlex

Oxidation of quinoxalineaminothiol with SCl 2 or S 2 Cl 2 /Cl 2 affords a series of compounds based on the quinoxaline-1,2,3-dithiazole framework QDTA. Under highly oxidizing conditions, the 1,2,3-dithiazolyl ring is opened to afford the acyclic dichlorosulfimino-sulfenyl chlorides Cl x -QDTA-Cl 3 (x = 0, 1, 2). Reduction of these "trichloro" compounds leads to ring closure. For x = 2, reduction using S 2 Cl 2 affords the dithiazolylium chloride [Cl 2 -QDTA][Cl]. For all values of x, reduction with iodide ion (3 mol equiv) affords the corresponding dithiazolyl radical [Cl x -QDTA]. The radicals can be isolated in good yield in crude form, but attempts to purify them by vacuum sublimation lead to thermal degradation. The radicals have nonetheless been fully characterized by EPR spectroscopy, and the assignments of the observed hyperfine coupling constants cross-matched with those obtained by computation at the B3LYP/6-31G** level. The structures of the trichloro compounds Cl x -QDTA-Cl 3 (x = 1, 2) have been confirmed by X-ray crystallography. Crystal data: Cl-QDTA-Cl 3 , monoclinic, space group C2/c, a = 30.561(5) Å, b = 4.9764(9) Å, c = 22.247(4) Å, β = 131.822(14)°, V = 2521.4(8) Å 3 , Z = 8, R(F) = 0.043, and R w (F) [I [Formula: see text] σ (I)] = 0.049; Cl 2 -QDTA-Cl 3 , orthorhombic, space group Pnma, a = 18.627(12) Å, b = 6.848(4) Å, c = 10.926(7) Å, V = 1393.7(15) Å 3 , Z = 4, R(F) = 0.047, and R w (F) [I [Formula: see text] 3σ(I)] = 0.060.Key words: thiazyl radicals, molecular conductors, EPR spectroscopy, quinoxaline, DFT calculations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.082
Threshold uncertainty score0.991

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0100.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.219
Teacher spread0.203 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it