Community‐acquired <i>Moraxella catarrhalis</i> pneumonia in previously healthy children
Bibliographic record
Abstract
BACKGROUND: The aim of this study was to determine if Moraxella catarrhalis is a common cause of community acquired pneumonia in children with no chronic medical problems. A secondary goal was to describe the clinical features of children with M. catarrhalis pneumonia. METHODS: A systematic literature search was conducted for (i) case series of pediatric community-acquired pneumonia (CAP) where one or more diagnostic tests for M. catarrhalis were applied to all cases and (ii) case reports of previously healthy children with proven M. catarrhalis pneumonia. RESULTS: There were nine case series describing a total of 1,500 children with CAP. The number of children tested and yield was as follows: blood cultures 0/402 (0%); sputum cultures 15/157 (10%); nasopharyngeal, or postnasal cultures 129/521 (25%); sputum or nasopharyngeal cultures 0/74 (0%) (one study allowed either); nucleic acid amplification testing 2/100 (2%); serology 30/976 (3%). There were eight case reports of CAP with M. catarrhalis in previously well children. Children were ages 3 weeks to 7 years of age (median 14 months). Six of 8 (75%) children required mechanical ventilation. All survived. CONCLUSION: It is common to detect M. catarrhalis in upper respiratory secretions in children with pneumonia, but bacteremia or seroconversion is rare. There are only eight well-documented case reports CAP due to M. catarrhalis in previously well children, with there being no distinctive features in the eight cases described to date. This organism is likely a rare cause of CAP in previously healthy children.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.002 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".