Management of arrhythmias in patients with tetralogy of Fallot
Bibliographic record
Abstract
PURPOSE OF REVIEW: Patients with tetralogy of Fallot are subject to arrhythmic sequelae that substantially impact morbidity and mortality. This review focuses on recent advances in our understanding of the prevalence and types of arrhythmias encountered. Diagnostic and prognostic tools are considered and therapeutic options discussed. RECENT FINDINGS: Multicenter studies have characterized the arrhythmia burden, assessed the impact of implantable cardioverter-defibrillators, and generated a risk score for primary prevention. Left ventricular hemodynamics are increasingly recognized as important contributors to risk for sudden death. Arrhythmia circuits have been characterized, and the impact of pulmonary valve replacement on sudden death has been further questioned. Recent studies cast doubt on the value of right ventricular pacing alone for cardiac resynchronization and provide a rationale for biventricular pacing. SUMMARY: Supraventricular arrhythmias exceed ventricular arrhythmias in prevalence, as atrial fibrillation increases with the aging population. Sudden death is the leading cause of late mortality, although therapeutic advances may alter this profile. Combinations of factors should be considered in risk stratification schemes to select appropriate implantable cardioverter-defibrillator candidates. The role of concomitant intraoperative ablation during pulmonary valve replacement surgery remains to be defined. Cardiac resynchronization therapy, particularly biventricular pacing, offers promise, but requires careful study before widespread implementation.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.003 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".