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Record W2002569113 · doi:10.1159/000241474

Development of γ-Glutamyltranspeptidase Activity in Mouse Small Intestine: Influence of Cortisone and Thyroxine

2009· article· en· W2002569113 on OpenAlexafffund
Daniel Ménard, Christiane Malo, R. Caívert

Bibliographic record

VenueBiology of the Neonate · 2009
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicSulfur Compounds in Biology
Canadian institutionsUniversité de Sherbrooke
FundersMedical Research Council Canada
KeywordsWeaningInternal medicineEndocrinologyGestationFetusCortisoneSmall intestineBiologyMedicinePregnancy

Abstract

fetched live from OpenAlex

The fetal and postnatal development of gamma-glutamyltranspeptidase (gamma-GT) activity has been examined in the different parts of the mouse small intestine. At 17 days of gestation, gamma-GT is present in all intestinal thirds and a decreasing gradient of activity from the proximal to the distal segments is already established. From 17 days of gestation up to 5 days after birth, a dramatic fall of activity is observed in all segments. gamma-GT activity reaches adult level before weaning in the proximal segment while it increases only during the 3rd postnatal week in the middle and distal intestinal segments. Daily administration of cortisone acetate (25 microgram/g b.w./day) for 3 days to 8-day-old mice elicits a premature increase of gamma-GT activity in all intestinal thirds, the maximal increase being observed in the proximal segment. On the other hand, thyroxine (1 microgram/g b.w./day) has no or little effect on the normal development of gamma-GT activity.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.185
Threshold uncertainty score0.359

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.245
Teacher spread0.232 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations15
Published2009
Admission routes2
Has abstractyes

Explore more

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