Tumours and related lesions of the endocrine system of bony and cartilaginous fishes
Bibliographic record
Abstract
The literature pertaining to the prevalence and histopathology of endocrine cell and tissue tumours and related lesions (TRL) in bony and cartilaginous fishes is catalogued and reviewed in the context of the embryological origin of the various components of the endocrine system. Reports of TRLs of endocrine cells or tissues of fishes are relatively rare, and of these, most describe thyroid neoplasms that appear to be simple hyperplasia. The vast majority of published reports of endocrine TRLs in fishes are case‐studies, and thus, with a few notable exceptions, the aetiology of the lesions is unknown. The exceptions include the epizootics of thyroid neoplasms in introduced Pacific salmon in the Great Lakes, which appear to have an environmental aetiology, and epizootics of gonadal stromal cell neoplasms. The latter were all found in either hybrid species or highly inbred captive strains of fishes, suggesting a genetic involvement in the tumourigenesis. The possible aetiologies for the reported TRLs in wild and captive fish species are discussed, and various hypotheses proposing infectious agents, genetic factors and environmental contaminants are considered.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".