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Record W2004289411 · doi:10.1007/s00125-012-2797-5

Identification and analysis of murine pancreatic islet enhancers

2012· article· en· W2004289411 on OpenAlexafffund
Bryan Tennant, A. Gordon Robertson, Marabeth M. Kramer, Leping Li, Xuekui Zhang, Miami Beach, Nina Thiessen, Readman Chiu, Karen Mungall, Cheryl J. Whiting, Paul V. Sabatini, Appl Kim, Raphaël Gottardo, Marco A. Marra, Francis C. Lynn, Steven J.M. Jones, Pamela A. Hoodless, Brad G. Hoffman

Bibliographic record

VenueDiabetologia · 2012
Typearticle
Languageen
FieldMedicine
TopicPancreatic function and diabetes
Canadian institutionsBC Cancer AgencySimon Fraser UniversityUniversity of British ColumbiaCanada's Michael Smith Genome Sciences CentreChild and Family Research InstituteBC Children's HospitalSunny Hill Health Centre for Children
FundersNatural Sciences and Engineering Research Council of CanadaNational Institutes of HealthChild and Family Research InstituteGenome British ColumbiaCanadian Institutes of Health ResearchGenome CanadaCanada's Michael Smith Genome Sciences CentreNational Human Genome Research InstituteMichael Smith Health Research BC
KeywordsEnhancerPDX1BiologyFOXA2IsletEnhancer RNAsEpigeneticsPancreatic isletsGeneticsGeneCell biologyGene expressionTranscription factorEndocrinologyInsulin

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.010
Threshold uncertainty score0.391

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.273
Teacher spread0.258 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations65
Published2012
Admission routes2
Has abstractno

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