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Record W2006412612 · doi:10.1097/rti.0b013e31819724d9

Pulmonary Intravascular Lymphoma

2009· article· en· W2006412612 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJournal of Thoracic Imaging · 2009
Typearticle
Languageen
FieldMedicine
TopicCNS Lymphoma Diagnosis and Treatment
Canadian institutionsUniversity of OttawaOttawa Hospital
Fundersnot available
KeywordsMedicinePathologyIntravascular large B-cell lymphomaLymphomaLungLumen (anatomy)RituximabConstitutional symptomsLymphatic systemBiopsyRadiologyAutopsyDiseaseInternal medicine

Abstract

fetched live from OpenAlex

Intravascular lymphoma (IVL) is a rare form of non-Hodgkin lymphoma characterized by proliferation of malignant lymphoid cells limited to the lumen of small vessels. Clinical manifestations are nonspecific and result from vascular obliteration and hypoxia. The disease affects primarily the skin and central nervous system, often associated with rapid systemic dissemination and aggressive clinical course if appropriate therapy is not initiated early. Involvement of the lungs, kidneys, adrenal glands, and prostate may occur. Primary pulmonary IVL is exceedingly rare. We describe a case of primary pulmonary IVL in an HIV-positive man presenting with nonspecific constitutional symptoms. High-resolution computed tomography demonstrated centrilobular nodules with ground-glass attenuation and peribronchial ground-glass opacities. The diagnosis was confirmed by thoracoscopic biopsy and histologic findings consisted of accumulation of malignant lymphocytes within alveolar capillaries, pulmonary veins, and peribronchial arterioles. Immunohistochemistry confirmed positivity for CD20, a marker for B lymphocytes. Combined systemic chemotherapy including rituximab was started and resulted in significant clinical and radiologic improvement with long-term disease-free survival.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.970
Threshold uncertainty score0.382

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.309
Teacher spread0.299 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it