Knowledge of carbohydrate consumption does not alter natural killer cell activity following an acute bout of high-intensity aerobic exercise
Bibliographic record
Abstract
Carbohydrate consumption during strenuous aerobic exercise reportedly minimizes post-exercise suppression of the innate immune system. One of the most common measurements of innate immunity is natural killer cell activity (NKCA). It is not known whether actual carbohydrate consumption or merely the knowledge of carbohydrate consumption mediates alteration in NKCA. The purpose of the present investigation was to determine if knowledge of carbohydrate beverage could result in alteration of RPE and NKCA, independent of actual carbohydrate intake. We recruited 11 male and female endurance athletes and randomly assigned them to either a correct or false knowledge of carbohydrate intake, such that in the false group, subjects were informed that they were receiving the carbohydrate beverage (CHO), but actually received a placebo (PLA) beverage. CHO and PLA beverages were matched to be similar in taste and appearance. Subjects completed 60 min of cycle ergometry (74% of VO2 peak). Venous blood samples were collected before (PRE), immediately after (POST), and 2 h after (2H) exercise and used to determine plasma glucose concentration, leukocyte total and differential counts, and NKCA. Data were statistically analyzed using a 3-factor analysis of variance (ANOVA) (p < 0.05). We did not find a significant effect of knowledge of drink type on leukocyte count, leukocyte differential, or NKCA. Drink type did not significantly alter leukocyte total, differential counts, or NKCA. There was a significant effect of exercise on NKCA. Knowledge of drink type does not alter innate immunity following exercise as assessed by leukocyte counts and NKCA.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".