Systemic Allergic Contact Dermatitis After Formaldehyde-Containing Influenza Vaccination
Bibliographic record
Abstract
BACKGROUND: Systemic contact dermatitis occurs when a patient sensitized to an allergen topically is systemically reexposed to the allergen and develops a cutaneous eruption. OBJECTIVE: To report the case of a 48-year-old male who developed explosive dermatitis following injection of a formaldehyde-containing influenza vaccine and was subsequently shown to be strongly positive to formaldehyde and formaldehyde-releasing allergens by patch testing, as well as to review the literature for similar cases. METHODS: A PubMed search was made using the following search terms: systemic contact dermatitis, formaldehyde, influenza, and vaccine. RESULTS: A review of the literature revealed 2 cases of systemic contact dermatitis from formaldehyde derived from aspartame and 1 case from a thimerosal-containing influenza vaccine. No cases caused by formaldehyde in influenza or other vaccines were found. CONCLUSION: This case highlights the importance of considering systemic allergic contact dermatitis in any patient presenting with dermatitis following injection of a formaldehyde-containing vaccine.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".