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Record W2010290000 · doi:10.1021/om060595s

Kinetics and Mechanisms of the Reactions of Diaryl- and Dialkylgermylenes with Alcohols and Ethers in Solution

2006· article· en· W2010290000 on OpenAlexaff
William J. Leigh, Farahnaz Lollmahomed, Cameron R. Harrington, Jacklyn M. McDonald

Bibliographic record

VenueOrganometallics · 2006
Typearticle
Languageen
FieldChemistry
TopicSynthesis and characterization of novel inorganic/organometallic compounds
Canadian institutionsMcMaster University
Fundersnot available
KeywordsChemistryFlash photolysisReaction rate constantLewis acids and basesMedicinal chemistryKineticsMethanolPhotochemistryOrganic chemistryCatalysis

Abstract

fetched live from OpenAlex

The reactions of methanol, tert -butanol, and THF with a series of simple germylene derivatives dimethyl- (GeMe 2 ), diphenyl- (GePh 2 ), and dimesitylgermylene (GeMes 2; Mes = 2,4,6-trimethylphenyl) have been studied in hexane solution at 25 °C by laser flash photolysis methods. The results are consistent with rapid, reversible reaction to form weakly stabilized Lewis acid−base complexes, which exhibit UV absorption maxima in the range 290−360 nm and decay with mixed order kinetics with concomitant formation of the corresponding digermene, Ge 2 R 4 (R = Me, Ph, or Mes). Absolute rate constants for formation of the complexes could be measured for GePh 2 with all three substrates and for GeMe 2 with THF and were found to vary over the range (4−10) × 10 9 M -1 s -1 . Equilibrium constants were measured in all cases; they vary between 1.2 and 15 M -1 for GeMes 2, decreasing in the order MeOH > t-BuOH > THF, while those for GeMe 2 and GePh 2 are 2−4 orders of magnitude larger and decrease in the order THF > MeOH > t-BuOH. For a given substrate, the equilibrium constants are consistently larger for GePh 2 than for GeMe 2, reflecting the greater ability of phenyl compared to methyl substituents to stabilize negative charge at germanium in the zwitterionic complexes. In spite of the differences in the stabilities of the complexes, the rate constant for complexation with THF is almost twice as large for GeMe 2 than for GePh 2 . The results indicate that the O−H insertion reaction of germylenes with alcohols proceeds via initial, reversible Lewis acid−base complexation, followed by slow proton transfer from oxygen to germanium, most likely via a catalytic route.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.202
Threshold uncertainty score0.428

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.187
Teacher spread0.179 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations34
Published2006
Admission routes1
Has abstractyes

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