Potentiation between Pentagastrin and Histamine in Stimulation of Secretion from Totally Isolated ex vivo Canine Stomach
Bibliographic record
Abstract
Totally isolated canine stomachs, perfused with homologous blood, were used for the study of potentiation between pentagastrin and histamine. These stimulants were infused into the gastric arterial system separately, or combined. Gastric secretion and perfusion blood were sampled every 30 min for biochemical analyses Combination of pentagastrin plus histamine gave significantly higher outputs of HCl than could be accounted for on the basis of summation of stimulatory effects. True potentiation, with regard to gastric juice volume and HCl output, occurred when two stimuli were infused simultaneously. Gastric hypersecretion of H+ was associated with increased O<sub>2</sub>–consumption by the stomach and by the alteration of the physiological relationship between the pH of arterial and venous blood sampled from gastric vessels. It was concluded that the totally isolated canine ex vivo stomach, perfused with homologous blood, is a suitable experimental preparation for the study of potentiation effects between two humoral gastric secretagogues.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".