Levels of antiangiogenic factors in preeclamptic pregnancies
Bibliographic record
Abstract
Preeclampsia is characterized by systemic maternal endothelial dysfunction that precedes the onset of clinical symptoms. Antiangiogenic factors are associated with preeclampsia. The aim of this study was to investigate the correlation between the levels of three antiangiogenic factors in preeclamptic pregnancies with/without fetal growth restriction (FGR), and to compare their level in early onset or late onset preeclampsia. Antiangiogenic factors, soluble endoglin (sEndoglin), sFlt-1, and placental growth factor (PIGF) were analyzed in healthy and preeclamptic women (including seven with FGR) at three different time points. sEndoglin or sFlt-1 but not PIGF levels were significantly higher in women with preeclampsia at admission. The level of sEndoglin was significantly higher in early onset, and higher in preeclamptic pregnancies with FGR compared to those without FGR. The level of sEndoglin was correlated with mean arterial pressure or 24-h urine protein in preeclampsia. Our data potentially suggest that Endoglin level correlates with the clinical symptoms of preeclampsia and preeclamptic pregnancies with FGR.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".