VITELLIFORM MACULAR DETACHMENT ASSOCIATED WITH BASAL LAMINAR DRUSEN IS UNRESPONSIVE TO VASCULAR ENDOTHELIAL GROWTH FACTOR BLOCKADE
Bibliographic record
Abstract
In Brief Purpose: To determine whether vascular endothelial growth factor (VEGF) mediates the leakage in basal laminar drusen (BLD)–associated vitelliform macular detachment (VMD) and whether VEGF blockade can improve visual function in affected eyes. Methods: Interventional case report. Patient: A 46-year-old woman presented with decreased visual acuity in the right eye and BLD-associated VMD. Results: There was no improvement in visual acuity, fundus appearance, or findings of fluorescein angiography and optical coherence tomography after two intravitreal injections of anti-VEGF agents, suggesting that the exudation is not VEGF mediated. Conclusion: Ophthalmologists should distinguish BLD-associated VMDs from age-related macular degeneration–associated choroidal neovascularization to avoid exposing patients to the risk of unnecessary intravitreal injections. The authors treated a patient with basal laminar drusen-associated vitelliform macular detachment with intravitreal anti-vascular endothelial growth factor (VEGF) agents to determine whether VEGF mediates the leakage in this disorder and whether these agents can improve visual function in affected eyes.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".