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Structural features of mossy cells in the hamster dentate gyrus, with special reference to somatic thorny excrescences

2000· article· en· W2014458114 on OpenAlexfundno aff
Ryo Murakawa, Toshio Kosaka

Bibliographic record

VenueThe Journal of Comparative Neurology · 2000
Typearticle
Languageen
FieldNeuroscience
TopicPhotoreceptor and optogenetics research
Canadian institutionsnot available
FundersNational Institute for Physiological SciencesVector Institute
KeywordsBiologyDentate gyrusLucifer yellowAnatomyHamsterNeuroscienceMossy fiber (hippocampus)Cell biologyHippocampusIntracellularMolecular biologyGap junction

Abstract

fetched live from OpenAlex

We have recently revealed that large multipolar neurons, presumed mossy cells in the hamster dentate gyrus (DG), were calretinin (CR)-immunoreactive (IR) at the ventral level, although these neurons were CR-negative at the dorsal level. In the present study, we confirmed this identification with several methods and analyzed structural features of hamster mossy cells in detail. Golgi impregnationi and intracellular Lucifer yellow labeling studies revealed that mossy cells in the hamster dentate hilus had extraordinarily prominent thorny excrescences on their somata as well as on their proximal dendrites. Mossy cells exhibited dorsoventral differences in their structural features; proximal dendrites of single mossy cells were fewer, and thorny excrescences were larger and more complicated at the dorsal level than at the ventral level. Electron microscopic serial section three-dimensional reconstructions revealed that somatic thorny excrescences consisted of large and complicated spines, which received numerous asymmetrical synapses from mossy fiber terminals. In addition, our confocal laser scanning microscopic observations also revealed many glutamic acid decarboxylase-immunoreactive punctae abutting the mossy cell somata and dendrites. Our present and previous observations revealed the structural features of hamster mossy cells and their differences along the dorsoventral axis and further indicated that mossy cells were prominently different in their chemical and morphological features among species.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.182
Threshold uncertainty score0.393

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.075
GPT teacher head0.351
Teacher spread0.275 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations20
Published2000
Admission routes1
Has abstractyes

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