MétaCan
Menu
Back to cohort
Record W2014785305 · doi:10.1021/ma901530r

Polymer Scaffolds for Biomaterials Applications

2009· article· en· W2014785305 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueMacromolecules · 2009
Typearticle
Languageen
FieldEngineering
Topic3D Printing in Biomedical Research
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsBiomaterialRegenerative medicineScaffoldTissue engineeringBiomoleculeNanotechnologyRegeneration (biology)Stem cellBiomedical engineeringMaterials scienceChemistryCell biologyEngineeringBiology

Abstract

fetched live from OpenAlex

Biomaterials have been used extensively in medical, personal care, and food applications, with many similar polymers being used across disciplines. This Perspective will emphasize polymers used in medicine and specifically those designed as scaffolds for use in tissue engineering and regenerative medicine. The areas of active research in tissue engineering include: biomaterials design—incorporation of the appropriate chemical, physical, and mechanical/structural properties to guide cell and tissue organization; cell/scaffold integration—inclusion into the biomaterial scaffold of either cells for transplantation or biomolecules to attract cells, including stem cells, from the host to promote integration with the tissue after implantation; and biomolecule delivery—inclusion of growth factors and/or small molecules or peptides that promote cell survival and tissue regeneration. While a significant and growing area of regenerative medicine involves the stimulation of endogenous stem cells, this Perspective will emphasize polymer scaffolds used for delivery of cells and biomolecules. The challenges and solutions pursued in designing polymeric biomaterial scaffolds with the appropriate 3-dimensional structure will be explored.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.280
Threshold uncertainty score0.352

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.281
Teacher spread0.268 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it