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Case Report: Pulmonary Nocardiosis in a Patient with Chronic Obstructive Pulmonary Disease and Receiving Corticosteroid Treatment due to Nephrotic Syndrome.

2015· article· en· W2015032638 on OpenAlexvenueno aff
Gülfem Ece, Adnan Tolga Öz, Ayşegül Baysak, Erkan Melih Şahi̇n

Bibliographic record

VenueGlobal Journal of Pathology and Microbiology · 2015
Typearticle
Languageen
FieldMedicine
TopicActinomycetales infections and treatment
Canadian institutionsnot available
Fundersnot available
KeywordsMedicinePulmonary diseaseNephrotic syndromeCorticosteroidInternal medicine

Abstract

fetched live from OpenAlex

Introduction : Nocardia spp. belong to Actinomycetes family and usually found in soil. They show variation in acid fast stain. Microscobic examination reveals Gram positive filamentous bacilli. Nocardiosis, is a rare clinical situation caused by Nocardia species and takes place especially in immunosuppressed individuals. In our case report we aimed to present pulmonary nocardiosis in a patient receiving corticosteroid treatment due to nephrotic syndrome and also accompanying chronic obstructive pulmonary disease. Case Presentation : 53 year old male patient was admitted to the Chest Diseases outpatient clinic with fever, sputum and cough complaints. The patient had a previous story of nephrotic syndrome and chronic obstructive pulmonary disease and receiving corticosteroid treatment. Thorax CT image showed a 13 cm cavitary lesion at the lower lobe of the right lung, and 21 mm lesion neighboring to the other lesion. Fibrotic structure was detected on both hilus of the lung. This was evaluated as a sequela of infection. The patient underwent flexible bronchoscopy and respiratory tract specimens (bronchoalveolar lavage, bronchial lavage and sputum) were sent to the Microbiology Laboratory. The Gram stain showed filamentous Gram positive bacilli and on the fourth day of incubation Nocardia spp was reported. The patient was administered trimethoprim sulfamethoxazole treatment and recovered. Discussion : Pulmonary nocardiosis is a rare disease. The importance of this infectious pathogen has increased due to recent increase immunosuppressive treatment modalities, HIV infection, and organ transplantation. The clinical and radiological symptoms are nonspecific and because of this microbiological methods are important in diagnosis of nocardiosis. Consecutive examination of clinical material showing the typical microscopic appearance in these patients should draw the attention of the clinician to this pathogen and treatment is needed to be done accordingly.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.035
Threshold uncertainty score0.543

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.244
Teacher spread0.233 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2015
Admission routes1
Has abstractyes

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