Review: antidepressants and psychotherapy may be equally effective for promoting remission in major depressive disorder
Bibliographic record
Abstract
Casacalenda N, Perry C, Looper K. Remission in major depressive disorder: a comparison of pharmacotherapy, psychotherapy, and control conditions. Am J Psych2002 Aug; 159 : 1354 –60. [OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] QUESTION: How do anti-depressants and psychotherapy compare in generating full remission in major depressive disorder? Systematic review with meta-analysis. Studies were identified using Medline and PsychInfo (to November 2000). Eligible studies were randomised controlled trials with blinded participants and assessors that (1) directly compared medications, psychotherapy and controls for well defined major depressive disorder; (2) included remission data. 6 studies were included with 883 outpatients with mild to moderate non-psychotic major depressive disorder. Mean age ranged from 32–40 years; 77% women (range 68–85%). Median treatment duration was 16 weeks (range 10–34). Data were extracted on baseline measurements, sample size, … [1]: {openurl}?query=rft.jtitle%253DAmerican%2BJournal%2Bof%2BPsychiatry%26rft.stitle%253DAm.%2BJ.%2BPsychiatry%26rft.aulast%253DCasacalenda%26rft.auinit1%253DN.%26rft.volume%253D159%26rft.issue%253D8%26rft.spage%253D1354%26rft.epage%253D1360%26rft.atitle%253DRemission%2Bin%2BMajor%2BDepressive%2BDisorder%253A%2BA%2BComparison%2Bof%2BPharmacotherapy%252C%2BPsychotherapy%252C%2Band%2BControl%2BConditions%26rft_id%253Dinfo%253Adoi%252F10.1176%252Fappi.ajp.159.8.1354%26rft_id%253Dinfo%253Apmid%252F12153828%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1176/appi.ajp.159.8.1354&link_type=DOI [3]: /lookup/external-ref?access_num=12153828&link_type=MED&atom=%2Febmental%2F6%2F2%2F45.atom [4]: /lookup/external-ref?access_num=000177327300014&link_type=ISI
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.005 | 0.025 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.009 | 0.006 |
| Bibliometrics | 0.007 | 0.008 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.004 | 0.002 |
| Open science | 0.002 | 0.001 |
| Research integrity | 0.003 | 0.002 |
| Insufficient payload (model declined to judge) | 0.011 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".