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Record W2015901170 · doi:10.1159/000046190

Evidence for Functional Partitioning of the Rabbit Digastric Muscle

2001· article· en· W2015901170 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueCells Tissues Organs · 2001
Typearticle
Languageen
FieldNeuroscience
TopicTranscranial Magnetic Stimulation Studies
Canadian institutionsUniversité de MontréalMcGill University
Fundersnot available
KeywordsDigastric muscleAnatomyMasticatory forceMasticationMuscles of masticationMandible (arthropod mouthpart)BiologyConnective tissueLateral pterygoid muscleMedicineCondylePathology

Abstract

fetched live from OpenAlex

The rabbit digastric muscle has a single belly that opens and retracts the mandible. It does not contain connective tissue partitions, and all fibers arise from the same tendon and insert into a single broad site. Historically, it was assumed that the muscle functioned as a single unit. Since we had preliminary evidence that this might not be the case, we carried out five small studies in rabbits. First, we showed that electromyographic (EMG) activity varies between recording sites within the muscle during the masticatory cycle induced by repetitive stimulation of the sensorimotor cortex. We found that EMG activity in the caudal region sometimes began before the anterior EMG during mastication when the jaw swung to the side of the muscle, but the two regions became active at the same time during other patterns. We next showed that separate branches of the mylohyoid nerve enter the anterior, intermediate and caudal regions of the digastric. However, a separate study showed that the motor endplates were distributed across a continuous sheet, consistent with a single anatomical partition. We then stimulated single nerve branches to deplete glycogen. By comparing the optical density of fibers labeled by the periodic acid-Schiff method for glycogen, we were able to show that the three branches innervate separate regions of the muscle. Finally, we applied either FluoroGold or Fast Blue dyes to the central cut ends of the branches to label the cell bodies of the three pools of motoneurons. These were found within the middle and caudal thirds of the trigeminal motor nucleus, but there appeared to be no spatial separation of the three pools or double labeling of cells. We conclude that the digastric muscle contains two and possibly three functional subregions. The fact that the motoneurons are intermingled suggests that the distribution of motor commands to the three pools is not based on their location.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.320
Threshold uncertainty score0.644

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.153
GPT teacher head0.306
Teacher spread0.154 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it