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Record W2016547258 · doi:10.4021//jmc.v3i1.397

Reversal of Heart and Respiratory Failure Following Accidental Exposure to Hydrogen Sulfide: Case Report

2012· article· en· W2016547258 on OpenAlexvenueno aff
David R. Silva, Nuno Correia, Miguel Marques, Gustavo Carrijo Barbosa, Carla Melo, Mário Esteves, Augusto Duarte

Bibliographic record

VenueJournal of Medical Cases · 2012
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicSulfur Compounds in Biology
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineHydrogen sulfideRespiratory failureIntensive care medicineAnesthesiaSulfur

Abstract

fetched live from OpenAlex

Risks of exposure to toxic gases are well recognized during work in sewers, the principal hazards resulting from hypoxia due to the accumulation of methane, carbon dioxide, or hydrogen sulfide and explosive risk as a result of flammable gases. Hydrogen sulfide ( H 2 S ) is a colourless rotten egg odour gas resulting from organic matter decomposition. The severity of H 2 S intoxication depends on the concentration and duration of exposure and the outcome may be fatal. We report the case of a 59-year-old male patient who was acutely exposed to sewers gases following an accidental leak in a swine facility nearly eighteen hours before. He presented to the emergency room with respiratory complaints and chest pain, and rapidly developed a multi-organ dysfunction syndrome with severe cardio-respiratory failure. No methaemoglobinemia was detected and H 2 S was presumed to be the major implicated toxic substance. Treatment strategy relied mostly on supportive measures with a successful outcome. Approach to victims of exposure to sewers gases should recall the strong possibility of poisoning by H 2 S , a life-threatening condition. Since laboratorial dosing of sulfide compounds is not readily available, the initial approach is based on a high clinical suspicion. H 2 S direct toxicity and cellular hypoxic induction may rapidly lead to multi-organic dysfunction and death. Evidence from case reports suggests that early treatment with nitrites, hyperbaric oxygen therapy and hydroxocobalamin may be beneficial. To the present date, supportive treatment remains the mainstay of care. doi:10.4021/jmc397w

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.008
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.003
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0020.001
Science and technology studies0.0020.002
Scholarly communication0.0020.002
Open science0.0010.002
Research integrity0.0080.005
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.314
Teacher spread0.292 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2012
Admission routes1
Has abstractyes

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