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Record W2017264178 · doi:10.1097/mcg.0b013e3181e5d1c5

Patients With IBD are Exposed to High Levels of Ionizing Radiation Through CT Scan Diagnostic Imaging

2010· article· en· W2017264178 on OpenAlexaff
Karen I. Kroeker, Simon Lam, Iain Birchall, Richard N. Fedorak

Bibliographic record

VenueJournal of Clinical Gastroenterology · 2010
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicInflammatory Bowel Disease
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsMedicineIonizing radiationNuclear medicineRadiologyMedical imagingRadiation exposureInflammatory bowel diseaseUlcerative colitisMalignancyRetrospective cohort studyDiseaseInternal medicineIrradiation

Abstract

fetched live from OpenAlex

GOALS: The objective of this study was to assess the total effective dose of ionizing radiation from abdominal diagnostic imaging in patients with inflammatory bowel disease (IBD) over a 5-year period. BACKGROUND: Radiation exposure from diagnostic imaging is becoming increasingly common in IBD patients, in part due the availability of computed tomography (CT). Increased risk of malignancy has been associated with radiation exposure. STUDY: This is a retrospective chart review. A university-based gastroenterology database was searched for patients with a diagnosis of Crohn's disease (CD) or ulcerative colitis (UC) seen between 2003 and 2008. The cumulative ionizing radiation exposure, expressed in milli-Sieverts (mSv), was then calculated from standard tables and by counting the number of abdominal imaging studies. RESULTS: Patients with CD had higher cumulative radiation exposure from diagnostic imaging than patients with UC (14.3 ± 1.45 mSv/5-y period vs. 5.9 ± 0.81 mSv/5-y period, P=0.00003). Three-quarters of the radiation exposure in both CD and UC was from CT scans. Thirty-four percent (127 of 373) of CD patients had CT scans, compared with just 20% (37 of 182) of UC patients. Importantly, 7% of CD patients were exposed to high levels of radiation (>50 mSv/5 y), in contrast to none of the UC patients. CONCLUSIONS: Patients with IBD, and especially CD patients, undergo frequent diagnostic imaging and thus significant exposure to ionizing radiation. This radiation exposure reaches high levels in 7% of CD patients, mainly from CT scanning. Efforts should be made to minimize the radiation exposure from diagnostic imaging by reducing either the number of studies or radiation dose in modalities with ionizing radiation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.473

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.291
Teacher spread0.277 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations113
Published2010
Admission routes1
Has abstractyes

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