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The Effect of Concurvity in Generalized Additive Models Linking Mortality to Ambient Particulate Matter

2003· article· en· W2017372646 on OpenAlexaff
Tim Ramsay, Richard T. Burnett, Daniel Krewski

Bibliographic record

VenueEpidemiology · 2003
Typearticle
Languageen
FieldEnvironmental Science
TopicAir Quality and Health Impacts
Canadian institutionsUniversity of OttawaHealth CanadaCanadian Mathematical Society
Fundersnot available
KeywordsMulticollinearityStatisticsCardiorespiratory fitnessEconometricsVariance (accounting)Series (stratigraphy)ParticulatesComputer scienceMathematicsRegression analysisMedicine

Abstract

fetched live from OpenAlex

In recent years, a number of studies have applied generalized additive models to time series data to estimate associations between exposure to air pollution and cardiorespiratory morbidity and mortality. If concurvity, the nonparametric analogue of multicollinearity, is present in the data, statistical software such as S-plus can seriously underestimate the variance of fitted model parameters, leading to significance tests with inflated type 1 error. This paper uses computer simulation and analyses of actual epidemiologic data to explore this underestimation of standard errors. We provide a method for assessing concurvity in data and an alternate class of models that is unaffected by concurvity. We argue that some degree of concurvity is likely to be present in all epidemiologic time series datasets and we explore through the use of meta-analysis the possible impact of concurvity on the existing body of work relating ambient levels of sulfate particles to mortality.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.249
metaresearch head score (Gemma)0.463
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.751
Threshold uncertainty score0.926

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.2490.463
Meta-epidemiology (narrow)0.0040.002
Meta-epidemiology (broad)0.0070.018
Bibliometrics0.0050.009
Science and technology studies0.0030.006
Scholarly communication0.0060.005
Open science0.0040.010
Research integrity0.0040.005
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.085
GPT teacher head0.378
Teacher spread0.293 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designSimulation or modeling
DomainMethods
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations258
Published2003
Admission routes1
Has abstractyes

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