Sleep-wake and circadian-dependent variation of cardiorespiratory coherence
Bibliographic record
Abstract
The risk of adverse cardiovascular events is elevated in the morning compared to the rest of the day. A circadian and a sleep-wake dependent variation in the regulation of the cardiovascular system could contribute to this increased cardiovascular risk. Using an ultradian sleep-wake cycle (USW) procedure, our aim was to explore the effects of the sleep-wake and circadian cycles on cardiorespiratory coherence (CRC) as a measure of autonomic nervous system (ANS) state. Our results suggest a shift toward parasympathetic dominance with deepening of sleep. Conversely, REM sleep is associated with a sympathetic dominance comparable to levels observed during wakefulness. A circadian rhythm was observed for CRC during wakefulness and all sleep stages. Maximal sympathetic dominance was observed in the morning, as measured by CRC during wakefulness and REM sleep, consistent with studies showing increased cardiac risk in the morning. This study provides evidence that circadian and sleep processes interact to influence the ANS modulation of the heart.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".