A corticosteroid-responsive aneurysmal lenticulostriate vasculopathy
Bibliographic record
Abstract
Primary angiitis of the CNS (PACNS) was initially described as granulomatous angiitis in 1952.1 Though it has been successfully treated with a combination of corticosteroids and cyclophosphamide,2 definitive diagnosis is difficult and clinicians are often reluctant to initiate toxic immunosuppressants without a clear diagnosis. Isolated involvement of the lenticulostriate arteries is not reported in PACNS. Furthermore, aneurysm formation is rare in PACNS although more common in systemic vasculitides.3 We describe a woman with a symptomatic lenticulostriate vasculopathy presumed to be PACNS. The disease progressed until the institution of immunosuppressive therapy and regressed once treated. ### First presentation. A 43-year-old woman presented in September 1999 with a left hemiparesis. She was normotensive with normal general examination. She had been healthy with no constitutional, rheumatologic, or neurologic symptoms. There were no stroke risk factors. CT demonstrated a right internal capsule lacunar infarction and several more infarcts bilaterally within the lenticulostriate territories. Angiography demonstrated subtle irregularities of the lenticulostriate arteries. …
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.002 | 0.002 |
| Insufficient payload (model declined to judge) | 0.005 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".