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Record W2018883334 · doi:10.1136/bmj.d5196

Persistent fever and rash in a young child

2011· article· en· W2018883334 on OpenAlexaff
P. J. Gill, David Burgner, A. Harnden

Bibliographic record

VenueBMJ · 2011
Typearticle
Languageen
FieldMedicine
TopicKawasaki Disease and Coronary Complications
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsMedicineRashIrritabilityMaculopapular rashCervical lymphadenopathyPhysical examinationPediatricsMedical historyDermatologyFamily historySurgeryDiseaseInternal medicine

Abstract

fetched live from OpenAlex

A 22 month old white Australian boy presented to his general practitioner with irritability, red eyes, and a two day history of high fever (highest at 41°C) that did not respond to paracetamol and ibuprofen. He had no history of cough, coryza, or rash. His medical history was unremarkable and immunisations were up to date. On examination, he had bilateral non-exudative conjunctival injection and was diagnosed with a non-specific febrile illness with associated conjunctivitis. His family then took him on a planned family holiday to Thailand where his conjunctivitis improved, but the fevers continued unabated. In addition to the fevers, his parents noted a mild nappy rash. On day 8 of the illness, his parents took him to a local clinic after a couple of episodes of diarrhoea. He was diagnosed with gastroenteritis. Later that day he became more unwell with increasing irritability and a progressive rash so his parents took him to hospital. He was dehydrated and lethargic and physical examination showed cervical lymphadenopathy, fissured lips, and an injected pharynx. His hands and feet were oedematous and his legs were covered in a pink maculopapular rash. Blood tests showed leucocytosis and increased acute phase reactants, but other haematological markers were normal. A chest radiograph was normal. He was admitted with presumed bacterial sepsis and started on broad spectrum intravenous antibiotics. However, after two days of antibiotics, his symptoms did not improve. ### 1 What is the most likely diagnosis in this case? #### Short answer Kawasaki disease. #### Long answer The most likely diagnosis is Kawasaki disease. Differential diagnoses to be considered in a child with a history of …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0020.001
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.038
GPT teacher head0.279
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2011
Admission routes1
Has abstractyes

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