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Record W2019820613 · doi:10.1002/hipo.20159

Retrograde amnesia following hippocampal lesions in the shock-probe conditioning test

2006· article· en· W2019820613 on OpenAlexaff
Hugo Lehmann, Valerie Lecluse, Andrea Houle, Dave G. Mumby

Bibliographic record

VenueHippocampus · 2006
Typearticle
Languageen
FieldNeuroscience
TopicMemory and Neural Mechanisms
Canadian institutionsConcordia UniversityUniversity of Lethbridge
Fundersnot available
KeywordsRetrograde amnesiaHippocampal formationAmnesiaFear conditioningPsychologyNeuroscienceAnterograde amnesiaHippocampusStimulus (psychology)ConditioningMemory disorderAnesthesiaClassical conditioningMedicineCognitive psychologyCognitive disorderCognitionAmygdala

Abstract

fetched live from OpenAlex

The present experiment examined the role of the hippocampal formation (HPC) in long-term memory of an association between an object and a fear-eliciting event. Rats either received sham or neurotoxic lesions of the HPC 1 or 14 days after learning that contacting a wire-wrapped probe (i.e., object) elicits a shock. After recovery from the surgery, rats were re-exposed to the wire-wrapped probe and burying and avoidance of the probe were assessed and used as memory and fear indices. Regardless of the learning-to-surgery interval, the rats with hippocampal lesions buried and avoided the probe significantly less than sham rats and no more than rats that never experienced shock from the probe. These findings suggest that the lesions caused severe retrograde amnesia and that the HPC has a long-lasting role in memory of a discrete stimulus associated with a fear-eliciting event.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.194
Threshold uncertainty score0.751

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.046
GPT teacher head0.291
Teacher spread0.245 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations23
Published2006
Admission routes1
Has abstractyes

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