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Record W2019884627 · doi:10.1136/bmj.e461

A 90 year old man with difficulty swallowing and proximal muscle weakness

2012· article· en· W2019884627 on OpenAlexaff
Habib Rehman

Bibliographic record

VenueBMJ · 2012
Typearticle
Languageen
FieldMedicine
TopicMyasthenia Gravis and Thymoma
Canadian institutionsRegina Qu'Appelle Health Region
Fundersnot available
KeywordsMedicineWeaknessDysphagiaMuscle weaknessIsometric exerciseProximal muscle weaknessPhysical examinationAnkleCranial nervesSurgeryAnatomyPhysical therapyInternal medicineMuscle biopsy

Abstract

fetched live from OpenAlex

A 90 year old man presented with progressive dysphagia, generalised weakness, and malaise. He had lost 30 lb (13.6 kg) in the past six months, and his mobility had deteriorated because of progressive leg weakness. He had no visual or constitutional symptoms apart from weight loss and denied any bladder or bowel problems. He had a 25 pack year history of smoking and did not drink alcohol. Examination showed signs consistent with bilateral pneumonia. His speech was dysphonic, the gag reflex was absent, but other cranial nerves were intact. He had wasting and weakness of the small muscles of the hands and weakness of the proximal muscles of the lower limbs. Reflexes were absent in the lower limbs. Strength in the remaining muscle groups—including ankle dorsiflexion, planter flexion, knee extension, and flexion—was normal. Proximal muscle groups in the upper extremity were strong, although reflexes were reduced bilaterally. No fasciculations were seen and he had no evidence of fatigable ptosis. Sensory examination was normal. Examination of the cardiovascular and abdominal systems was unremarkable. Investigations showed a white blood cell count of 5.9×109 cells/L (reference range 4.0-10.0), haemoglobin 117 g/L (140-180), platelets 332×109 (320-360), random glucose 10.8 mmol/L (3.6-11), urea 25.3 mmol/L (3.0-7.1), creatinine …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0020.001
Scholarly communication0.0010.002
Open science0.0010.001
Research integrity0.0030.003
Insufficient payload (model declined to judge)0.0030.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.267
Teacher spread0.252 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2012
Admission routes1
Has abstractyes

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