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Efecto de la maniobra inspiratoria y de la hiperinsuflación pulmonar en los flujos espiratorios máximos en pacientes con fibrosis quística

2003· article· es· W2020139570 on OpenAlexaff
Ignacio Sánchez D, Marta Simonetti, Jan De Koster, Victor Chernick

Bibliographic record

VenueRevista chilena de enfermedades respiratorias · 2003
Typearticle
Languagees
FieldMedicine
TopicInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Canadian institutionsUniversity of Manitoba
Fundersnot available
KeywordsMedicineHumanitiesPhilosophy

Abstract

fetched live from OpenAlex

El tiempo inspiratorio previo a la realizacion de una maniobra espiratoria forzada maxima (FEM) es una variable que no ha sido completamente estudiada en Fibrosis Quistica (FQ). El objetivo de este estudio fue evaluar la hipotesis que ninos con FQ tendrian mayores volumenes y flujos espiratorios forzados al disminuir la duracion del tiempo inspiratorio. Se estudiaron 16 ninos con FQ, en etapa estable, sin haber presentado una exacerbacion respiratoria en los ultimos dos meses, (10 hombres), de edad 11,9 ± 0,7 anos (promedio ± ES), con un FEV1 de 62,8 ± 6,4% predicho. Las pruebas de funcion pulmonar consistieron en la medicion de volumenes pulmonares estaticos y resistencia de la via aerea, seguido de evaluacion dinamica de la funcion pulmonar. Esta ultima medicion fue precedida de 3 maniobras inspiratorias diferentes en forma aleatoria [inspiracion y detencion de 0 segundos (M0), 2 segundos (M2) o 5 segundos (M5)]. El grupo se dividio en pacientes con hiperinsuflacion pulmonar detectada por VR/CPT > 30%, (n = 9) y sin hiperinsuflacion pulmonar RV/CPT < 30% (n = 7). Los resultados demostraron que, en los pacientes con hiperinsuflacion, VEF1 y CVF fueron 8,9 ± 3,4% (p < 0,02) y 9,3 ± 2,1% (p < 0,001) mayores respectivamente, despues de M0 en comparacion a despues de M2 y 2,4 ± 2,8% (p = ns), y 2,8 ± 3,2% (p = ns) menor respectivamente despues de M5 en relacion a despues de M2 (M0 vs M5: p < 0,01 para ambos, VEF1 y CVF). En resumen, en pacientes portadores de Fibrosis Quistica e hiperinsuflacion, VEF1 y CVF son significativamente mayores luego de realizar una espiracion sin detencion de inspiracion comparado a una detencion de inspiracion de 2 o 5 segundos. Sugerimos que los mecanismos de relajacion de la musculatura lisa del arbol bronquial pueden ser los responsables de este hallazgo.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.289
Teacher spread0.283 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2003
Admission routes1
Has abstractyes

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