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Record W2023659025 · doi:10.7202/010969ar

Claude Fortier : une grande histoire de la neuroendocrinologie

2005· article· fr· W2023659025 on OpenAlexaboutno aff
William Rostène

Bibliographic record

Venuemédecine/sciences · 2005
Typearticle
Languagefr
FieldNeuroscience
TopicStress Responses and Cortisol
Canadian institutionsnot available
Fundersnot available
KeywordsHumanitiesArtPhilosophy

Abstract

fetched live from OpenAlex

L’oeuvre de Claude Fortier est indissociable de l’histoire de la neuroendocrinologie. A travers ses travaux realises a Montreal avec Hans Selye, puis a Quebec dans son laboratoire ou se sont succedes de tres nombreux neuroendocrinologistes reputes, c’est toute la saga de la recherche sur le CRH (corticotropin releasing hormone) et la regulation de l’axe hypothalamo-hypophyso-surrenalien (HPA) ou axe du stress que l’on peut relater. Parmi les travaux pionniers de Claude Fortier, on peut citer la mise en evidence de la retroaction de l’activite centrale et hypophysaire de l’axe HPA par les glucocorticoides et la mise en evidence de recepteurs des glucocorticoides et des mineralocorticoides reglant distinctement la liberation d’ACTH (adrenocorticotropic hormone). On lui doit aussi d’avoir ete l’un des precurseurs dans l’utilisation de l’outil informatique en recherche biomedicale. Les retombees de ses decouvertes dans les maladies du stress (anxiete, depression, addiction) sont majeures. Claude Fortier ne fut pas seulement un grand homme de science, dont les travaux et ceux de ses collegues ont ete recompenses par de nombreux prix et distinctions, mais il a aussi joue un role politique important dans l’organisation de la recherche au Quebec dont la qualite est reconnue internationalement.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Science and technology studies
Consensus categoriesScience and technology studies
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.813
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0020.005
Scholarly communication0.0000.001
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.321
Teacher spread0.279 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2005
Admission routes1
Has abstractyes

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