406 EFFECT OF DIFFERENT FOLLICLE-STIMULATING HORMONE DOSES ON SUPEROVULATORY RESPONSE OF RED SINDHI COWS
Bibliographic record
Abstract
The use of bovine embryo transfer to increase the reproductive potential of animals with high genetic merit is unquestionable. However, studies that evaluate the response to exogenous FSH stimulation in Red Sindhi cows are rare. Therefore, the objective of this study was to compare the superovulatory response of Red Sindhi cows treated with 3 different doses of FSH (Folltropin®-V, Bioniche Animal Health, Belleville, Ontario, Canada). The animals used had body condition scores ranging from 3.5 to 4.0 (1-5 scale), were between 6 and 10 years of age, and were randomly assigned to 1 of 3 treatment groups. Three doses of FSH were administered: 100 mg (n = 16); 133 mg (n = 13), and 200 mg (n = 14). The treatments were initiated on random days of the estrous cycle. On Day 0, animals received 2 mg of estradiol benzoate i.m. (Estrogin®, Farmavet, Jaboticabal, Brazil) and an intravaginal device (CIDR; InterAg, Hamilton, New Zealand) with 1.9 g of progesterone. On Day 4, donors received FSH in 8 i.m. injections that decreased in dose during 4 consecutive days. A dose of 265 µg of cloprostenol (Ciosin®, Schering-Plough, Cotia, Brazil) was given i.m. concomitantly with the fifth FSH injection. Twelve hours after the last FSH injection, donors received 25 µg of lecirelin i.m. (GnRH; Gestran Plus®, ARSA SRL, Buenos Aires, Argentina). TheAI were performed 12 and 24 h after GnRH. Seven days after the first AI, embryos were recovered and classified as described in the IETS manual. Data were evaluated using KruskalWallis test at a 5% level of significance. Ovarian ultrasonography was also performed to count the number of CL present at the time of ova/embryo collection. Results are summarized in Table 1. The number of CL and total ova/embryos was higher in donors receiving 200 mg of FSH than in those in the other groups. However, the number of transferable or cryopreserved embryos did not differ among groups. In conclusion, the dosage of 200 mg of Folltropin®-V seemed to be the more adequate dosage for this breed of cattle. Table 1. Effect of different follicle-stimulating hormone (FSH) doses on CL number, total structures, transferable embryos, and cryopreserved embryos in Red Sindhi cows (mean ± SEM) Financial support provided by FAPERJ (E26-170.529/2007).
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".