Survival Outcomes of Early Stage Oral Cavity Squamous Cell Carcinoma: A Multi‐institutional Analysis
Bibliographic record
Abstract
Objectives: Surgical resection is the standard of care in early stage oral cavity squamous cell carcinoma (OCSCC). Recent literature has shown, however, that adverse pathologic features are potential indications for adjuvant radiotherapy. Objective: 1) Evaluate survival outcomes of early‐stage OCSCC patients. 2) Determine whether a subgroup of patients may benefit from adjuvant radiotherapy. Methods: The setting for this study was the two tertiary cancer centers in the province of Alberta and was designed as a prospective population‐based multi‐institutional review. Demographic, pathologic, treatment, and survival data was obtained from patients diagnosed with early stage OCSCC from 1998 to 2010. Survival outcomes were calculated using Kaplan‐Meir and Cox‐Regression analysis. Results: A total of 343 patients were analyzed. Five‐year survival according to treatment modality were surgery, 83.3 %; surgery + radiation, 94.7 %; radiation, 56.4 %. Cox regression analysis did not show any significant differences between groups when considering age, gender, and CCI/ECOG score. Conclusions: Patients with early stage OCSCC have excellent survival when treated by primary surgical resection. A subgroup of patients may benefit from post‐operative radiotherapy.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".