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Record W2024612421 · doi:10.1002/ajim.20407

Neurobehavioral functioning after cessation of manganese exposure: A follow‐up after 14 years

2006· article· en· W2024612421 on OpenAlexaffabout
Maryse F. Bouchard, Donna Mergler, Mary Baldwin, Michel Panisset, Rosemarie M. Bowler, Harry A. Roels

Bibliographic record

VenueAmerican Journal of Industrial Medicine · 2006
Typearticle
Languageen
FieldEnvironmental Science
TopicHeavy Metal Exposure and Toxicity
Canadian institutionsCentre Hospitalier de l’Université de MontréalUniversité du Québec à Montréal
Fundersnot available
KeywordsMedicineMoodCognitionCognitive testPhysical therapyPediatricsPsychiatry

Abstract

fetched live from OpenAlex

BACKGROUND: Little is known on the long-term course of early manganese (Mn) neurotoxic effects. Mn alloy workers were examined in a follow-up study 14 years after exposure ceased at a Canadian facility. METHODS: The same battery of neurofunctional tests used in the initial examination in 1990 was administered to 77 Mn-workers and 81 referents in 2004. RESULTS: Manganese-workers had poorer scores compared to referents both in the initial and follow-up examinations for several motor tasks of the Luria Motor Scale. At follow-up, older Mn-workers (>45 years at cessation of exposure) had poorer scores than referents for tests of cognitive flexibility. Cumulated exposure was associated with poorer test scores for certain neuromotor and cognitive tests and on a mood scale. Differences on certain tests observed at initial examination were not present at follow-up. CONCLUSIONS: Manganese exposure was associated with persistent deficits for certain neuromotor functions, cognitive flexibility, and adVerse mood states, while recovery occurred for other functions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.208
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.240
Teacher spread0.222 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations83
Published2006
Admission routes2
Has abstractyes

Explore more

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