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Can Policy Decisions in Transfusion Medicine Be Evidence‐Based?*

2003· article· en· W2026316445 on OpenAlexaff
Eleftherios C. Vamvakas, James P. AuBuchon

Bibliographic record

VenueTransfusion Alternatives in Transfusion Medicine · 2003
Typearticle
Languageen
FieldMedicine
TopicBlood transfusion and management
Canadian institutionsCanadian Blood ServicesUniversity of Ottawa
Fundersnot available
KeywordsTransfusion medicineMedicineIntervention (counseling)Psychological interventionScientific evidenceIntensive care medicineBlood transfusionActuarial scienceRisk analysis (engineering)PsychiatryEconomicsSurgery

Abstract

fetched live from OpenAlex

SUMMARy If the concept of evidence‐based medicine were considered at a policy level, it would likely dictate that policy decisions be made on the basis of the best available research evidence. In transfusion medicine, however, decisions are based on a broader range of inputs, and the criteria for evaluating the efficacy and/or cost‐effectiveness of proposed interventions differ from those used in other areas. Reasons why policy decisions in transfusion medicine are often based on considerations other than solely the best available research evidence include public perceptions of transfusion as being an inherently “unsafe” intervention, public expectations with regard to transfusion safety, and proposals for applying the precautionary principle to transfusion medicine. In the authors' opinion, use of the precautionary principle may be justified in addressing transfusion risks that are viewed as “dread events,” but this principle should not be applied indiscriminately to all transfusion risks.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.182
metaresearch head score (Gemma)0.513
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.818
Threshold uncertainty score0.962

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1820.513
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0030.002
Bibliometrics0.0050.004
Science and technology studies0.0030.018
Scholarly communication0.0250.021
Open science0.0050.006
Research integrity0.0380.025
Insufficient payload (model declined to judge)0.0150.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.086
GPT teacher head0.376
Teacher spread0.291 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
DomainMethods
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2003
Admission routes1
Has abstractyes

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