TREATMENT OF RETINITIS PIGMENTOSA—RELATED CYSTOID MACULAR EDEMA WITH INTRAVITREOUS RANIBIZUMAB
Why this work is in the frame
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Bibliographic record
Abstract
In Brief Purpose: To report the results of the use of intravitreous ranibizumab for treatment of cystoid macular edema (CME) associated with retinitis pigmentosa (RP). Methods: Intravitreous ranibizumab was used to treat a patient with CME associated with RP who was unable to tolerate oral acetazolamide and did not respond to topical dorzolamide treatment. Visual acuity, clinical examination, and optical coherence tomography (OCT) were performed before and after treatment. Results: Intravitreous ranibizumab improved best-corrected visual acuity (BCVA) and decreased central retinal thickness (CRT) with disappearance of cystic spaces on the OCT. There was recurrence of CME on discontinuation of injections. Conclusion: Intravitreous ranibizumab may be an effective therapy for reducing RP-related CME. Further studies are required to determine whether intravitreous ranibizumab is beneficial in the management of this disease. A 36-year old male with retinitis pigmentosa (RP)-related cystoid macular edema (CME) responded favorably to intravitreous ranibizumab, with resolution of CME and improved visual acuity. Three months after discontinuing treatment, CME recurred. Intravitreous ranibizumab may be an effective therapy for RP-related CME.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it