Bibliographic record
Abstract
45, X/46, XYdic mosaicism in both skin and blood is reported in a six-year-old child presenting at birth with ambiguous genitalia. Examination revealed a greatly enlarged clitoris with perineal hypospadias, a small vagina, and bilateral inguinal hernias containing palpable gonads. Laparotomy and histology demonstrated a normal uterus and tubes with ovotestes in ovarian position. Physical examination was otherwise normal; she had the expected average height and weight for her age and no detectable aberrations of behavior. The dicentric Y chromosome was diagnosed on the basis of direct examination, autoradiography, and fluorescence analysis. Xg-blood grouping confirmed a single, maternally derived Xg locus. Search of suitable metaphases from short blood cultures revealed 104 cells with 46, XYdic; 26 with 45, X; 1 with 47, XYYdic; 2 with 46, XY; and 2 with 47, XYdicYdic. Findings in the skin indicated that the majority of cells were of the 45, X type. Examination of the patient’s blood cells during anaphase and telophase revealed more cells with bridge formation or lagging chromosomes than those from the normal controls. Such observation and the described karyotypes suggest that, although the dicentric Y usually divides normally during mitosis, in certain instances it divides abnormally to give XO and other aberrant cells. Possible mechanisms which may lead to such an unusual chromosome constitution are discussed.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".