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Genome interplay in the grain transcriptome of hexaploid bread wheat

2014· article· en· 362 citations· W2028145262 on OpenAlex· 10.1126/science.1250091

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Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.

Machine scores (provisional)

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Opus teacher head0.014
GPT teacher head0.235
Teacher spread
0.221 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

Allohexaploid bread wheat (Triticum aestivum L.) provides approximately 20% of calories consumed by humans. Lack of genome sequence for the three homeologous and highly similar bread wheat genomes (A, B, and D) has impeded expression analysis of the grain transcriptome. We used previously unknown genome information to analyze the cell type-specific expression of homeologous genes in the developing wheat grain and identified distinct co-expression clusters reflecting the spatiotemporal progression during endosperm development. We observed no global but cell type- and stage-dependent genome dominance, organization of the wheat genome into transcriptionally active chromosomal regions, and asymmetric expression in gene families related to baking quality. Our findings give insight into the transcriptional dynamics and genome interplay among individual grain cell types in a polyploid cereal genome.

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The record

Venue
Science
Topic
Wheat and Barley Genetics and Pathology
Field
Agricultural and Biological Sciences
Canadian institutions
Funders
Bayer CropScienceGenome PrairieBiotechnology and Biological Sciences Research CouncilInstitut National de la Recherche AgronomiqueNorges ForskningsrådAgence Nationale de la RechercheTürkiye Bilimsel ve Teknolojik Araştırma KurumuFrance AgriMerBundesministerium für Bildung und ForschungMinistry of Agriculture, Forestry and FisheriesOffice of ScienceGrains Research and Development CorporationInternational Center for Agricultural Research in the Dry AreasKansas Wheat CommissionEuropean Molecular Biology LaboratoryArcadia FundScottish GovernmentRural and Environment Science and Analytical Services DivisionDeutsche ForschungsgemeinschaftMinistry of Agriculture - SaskatchewanGenome CanadaDirectorate for Biological SciencesJoint Genome InstituteGrantová Agentura České RepublikyGatsby Charitable FoundationWestern Grains Research FoundationU.S. Department of AgricultureEuropean CommissionU.S. Department of Energy
Keywords
TranscriptomeGenomeBiologyWheat grainGeneticsComputational biologyAgronomyGeneGene expression
Has abstract in OpenAlex
yes